Quantitative Studies on the Precipitin Reaction

نویسندگان

  • Michael Heidelberger
  • Forrest E. Kendall
  • Torsten Teorell
چکیده

1. Antisera to R-salt-azo-benzidine-azo-crystalline egg albumin give precipitates with crystalline egg albumin by virtue of their antidye content. 2. The quantitative course of the reactions with increasing amounts of antigen is very similar for the dye-antidye and egg albumin-anti-egg albumin systems, but differs markedly for the cross reaction between egg albumin and antidye. 3. A possible explanation for the occurrence of this one-sided crossreaction is given in terms of reactive groupings on the antigen and antibody. 4. A qualitative expression of the course of the cross-reaction is given in terms of the laws of classical chemistry.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Quantitative Studies on the Precipitin Reaction Effect of Salts on the P~eaction*

In the studies on the precipitin reaction hitherto published from this laboratory (1) the salt concentration was held constant at 0.9 per cent of sodium chloride in order to permit observations on the effect of varying the proportions of antigen (or hapten) and antibody. In the present paper are reported data obtained during several years on the influence on the course of the precipitin reactio...

متن کامل

Quantitative Studies on the Precipitin Reaction Effect of Salts on Tee Reaction*

In the studies on the precipitin reaction hitherto published from this laboratory (1) the salt concentration was held constant at 0.9 per cent of sodium chloride in order to permit observations on the effect of varying the proportions of antigen (or hapten) and antibody. In the present paper are reported data obtained during several years on the influence on the course of the precipitin reactio...

متن کامل

Studies on Photo-oxidation of Antigen and Antibodies

1. Quantitative precipitin studies indicate that progressive photo-oxidation progressively destroys the antigenic function of egg albumin. 2. Quantitative precipitin reactions of antisera (anti-egg albumin rabbit serum and antipneumococcus Type I horse serum) demonstrate that progressive photo-oxidation causes progressive lowering of the potency of the sera. 3. Quantitative precipitin reactions...

متن کامل

A Quantitative Study of the Cross Reaction of Types Iii and Viii Pneumococci in Horse and Rabbit Antisera

1. A preparation of the specific polysaccharide of Type VIII pneumococcus is described in which the use of heat, strong acid, and alkali were avoided. 2. Quantitative estimations are given of the homologous and cross reacting precipitin and agglutinin in Types III and VIII antisera produced in the rabbit and in the horse. Quantitative data are also given on the mechanism of the Type VIII precip...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 63  شماره 

صفحات  -

تاریخ انتشار 1936